bsm-90046R

DATASHEET

Host: Rabbit

Target Protein: Chromodomain Helicase DNA Binding Protein 4

Specificity: Knockdown Validated

Immunogen Range: 1800-1870/1912

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 1108

Swiss Prot: Q14839

Source: A synthesized peptide derived from human CHD4

Purification: Affinity Purified

Storage Buffer: Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Storage: -20 °C

Background:

ATP-dependent helicase that binds and distorts nucleosomal DNA. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Localizes to acetylated damaged chromatin in a ZMYND8-dependent manner, to promote transcriptional repression and double-strand break repair by homologous recombination.

Cell Line: HeLa

Knockdown technology: shRNA Knockdown

Size: 50 ul Ab + 25ug KD cell Lysate + 25ug WT cell

Concentration: Lot dependent

Predicted Molecular Weight: 218 kDa

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.