bsm-90005R

DATASHEET

Host: Rabbit

Target Protein: Microtubule Associated Protein 1 Light Chain 3 Alpha

Specificity: Knockdown Validated

Immunogen Range: 1-34/121

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 84557

Swiss Prot: Q9H492

Source: A synthesized peptide derived from human MAP1LC3A

Purification: Affinity Purified

Storage Buffer: Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Storage: -20 °C

Background:

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover.

Cell Line: HeLa

Knockdown technology: shRNA Knockdown

Size: 50 ul Ab + 25ug KD cell Lysate + 25ug WT cell

Concentration: Lot dependent

Predicted Molecular Weight: 14 kDa

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.