bsm-70160M

DATASHEET

Host: Mouse

Target Protein: Mitochondria

Specificity: Specific for endogenous levels of the ~60 kDa human mitochondria. The antibody works on acetone fixed and 2% paraformaldehyde fixed cells. The antibody also works for immunohistochemistry on 2% paraformaldehyde fixed (5-10 minutes) cryostat sections.

Clonality: Monoclonal

Isotype: IgG1

Source: Human cell homogenate

Purification: Purified by Protein A.

Storage Buffer: PBS

Storage: Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliq

Background:

Mitochondria are most commonly known as the power plants of the cell as they produce ATP, but they are also involved in many other important cellular processes such as cell signaling, growth and differentiation (McBride et al., 2006). In addition, mitochondria have been shown to play a role in apoptosis (Green 1998). This antibody is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells, including neurons and embryonic stem cells.

Size: 100ul

Concentration: Lot Dependent

Predicted Molecular Weight: 60

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.