bsm-70072M

DATASHEET

Host: Mouse

Target Protein: Doublecortin

Specificity: Specific for endogenous levels of the ~35 kDa & ~45 kDa doublecortin protein.

Clonality: Monoclonal

Isotype: IgG2a

Entrez Gene: 1641

Swiss Prot: O43602

Source: Full length recombinant human protein expressed in and purified from E. coli.

Purification: Purified by Protein G.

Storage Buffer: PBS + 50% glycerol and 5 mm NaN3

Storage: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Background:

Doublecortin, or DCX, is a microtubule associated protein that is expressed almost exclusively in very early neuronal development (Brown et al., 2003), making it an excellent marker for developing neuronal cells. Defects in the DCX gene lead to X-linked lissencephaly which is characterized by a lack of normal folds on the surface of the brain resulting in a smooth cerebral cortex caused by abnormal migration of neurons during development (des Portes et al., 1998; Gleeson et al., 1998).

Size: 100ul

Concentration: Lot Dependent

Predicted Molecular Weight: 35, 45

Cross Reactive Species: Human
Mouse
Rat
Bovine

For research use only. Not intended for diagnostic or therapeutic use.