Host: Rabbit
Target Protein: NPHS2
Clonality: Monoclonal
Isotype: IgG
Entrez Gene: 7827
Swiss Prot: Q9NP85
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Background:
Podocin is an important member of a group of proteins shown to be associated with the slit diaphragm. Podocin belongs to the band 7 stomatin family of lipid raft-associated proteins. It is a hairpin like integral membrane protein with intracellular N and C termini. Podocin is located at the insertion site of the slit membrane, and is thought to act as a scaffold protein required to maintain or regulate the structural integrity of the slit diaphragm. It plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton.
Conjugation: AbBy Fluor® 555
Excitation/ Emission: 553nm/568nm
Size: 100ul
Concentration: 1ug/ul
Applications: WB(1:500-2000)
Cross Reactive Species:
Human
Mouse
Rat
(42)
For research use only. Not intended for diagnostic or therapeutic use.