bsm-63001R

DATASHEET

Host: Rabbit

Target Protein: TRIM28 (Ser824)

Modification Site: Ser824

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 10155

Swiss Prot: Q13263

Source: KLH conjugated synthetic peptide derived from human TIF1 beta around the phosphorylation site of S824

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 89

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.