bsm-62889R

DATASHEET

Host: Rabbit

Target Protein: LRP6

Modification Site: Ser1490

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 4040

Swiss Prot: O75581

Source: KLH conjugated synthetic peptide derived from human LRP6 around the phosphorylation site of S1490

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 180

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.