bsm-62848R-Cy3

DATASHEET

Host: Rabbit

Target Protein: Syk

Modification Site: Tyr323

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 6850

Swiss Prot: P43405

Source: KLH conjugated synthetic peptide derived from human Syk around the phosphorylation site of Y323

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development.Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: Lot dependent

Applications: WB(1:300-5000)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 72

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.