bsm-62804R

DATASHEET

Host: Rabbit

Target Protein: Lunatic Fringe

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 3955

Swiss Prot: Q8NES3

Source: KLH conjugated synthetic peptide derived from human LFNG

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 42

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.