bsm-62800R

DATASHEET

Host: Rabbit

Target Protein: p45 NF-E2

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 4778

Swiss Prot: Q16621

Source: KLH conjugated synthetic peptide derived from human NFE2

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

Size: 100ul

Concentration: Lot dependent

Predicted Molecular Weight: 41

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.