bsm-62786R-FITC

DATASHEET

Host: Rabbit

Target Protein: HTRA1

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 5654

Swiss Prot: Q92743

Source: KLH conjugated synthetic peptide derived from human Serine protease HTRA1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space.

Conjugation: FITC

Excitation/ Emission: 494nm/518nm

Size: 100ul

Concentration: Lot dependent

Applications: WB(1:300-5000)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 51

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.