bsm-62560R-Biotin

DATASHEET

Host: Rabbit

Target Protein: ABRAXAS1

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 84142

Swiss Prot: Q6UWZ7

Source: KLH conjugated synthetic peptide derived from human ABRAXAS1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: Lot dependent

Applications: WB(1:300-5000)
IP(1-2ug)

Predicted Molecular Weight: 47

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.