bsm-62438R

DATASHEET

Host: Rabbit

Target Protein: RanBP3

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 8498

Swiss Prot: Q9H6Z4

Source: KLH conjugated synthetic peptide derived from human RanBP3

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner.

Size: 100ul

Concentration: Lot dependent

Predicted Molecular Weight: 60

Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.