bsm-62430R

DATASHEET

Host: Rabbit

Target Protein: Histone H2B type 2E

Modification Site: Lys12

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 8349

Swiss Prot: Q16778

Source: KLH conjugated synthetic peptide derived from human Histone H2B type 2E around the crotonylation site of K12

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Size: 100ul

Concentration: Lot dependent

Predicted Molecular Weight: 14

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.