bsm-62426R-Biotin

DATASHEET

Host: Rabbit

Target Protein: Histone H2B type 2E

Modification Site: Lys16

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 8349

Swiss Prot: Q16778

Source: KLH conjugated synthetic peptide derived from human Histone H2B type 2E around the acetylation site of K16

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: Lot dependent

Applications: WB(1:300-5000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IP(1-2ug)

Predicted Molecular Weight: 14

Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.