bsm-62290R

DATASHEET

Host: Rabbit

Target Protein: DBF4A

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 10926

Swiss Prot: Q9UBU7

Source: KLH conjugated synthetic peptide derived from human DBF4

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 77

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.