bsm-62264R-BF555

DATASHEET

Host: Rabbit

Target Protein: RYK

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 6259

Swiss Prot: P34925

Source: KLH conjugated synthetic peptide derived from human RYK

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.

Conjugation: AbBy Fluor® 555

Excitation/ Emission: 553nm/568nm

Size: 100ul

Concentration: Lot dependent

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 68

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.