bsm-62213R

DATASHEET

Host: Rabbit

Target Protein: MBNL1

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 4154

Swiss Prot: Q9NR56

Source: KLH conjugated synthetic peptide derived from human MBNL1

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 42

Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.