bsm-62207R

DATASHEET

Host: Rabbit

Target Protein: TIRAP

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 114609

Swiss Prot: P58753

Source: KLH conjugated synthetic peptide derived from human TIRAP

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Adapter involved in TLR2, TLR4 and RAGE signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha (TNF) and interleukin-6 (IL6).

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 24

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.