bsm-62172R

DATASHEET

Host: Rabbit

Target Protein: PRKRA

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 8575

Swiss Prot: O75569

Source: KLH conjugated synthetic peptide derived from human PRKRA

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Activates EIF2AK2/PKR in the absence of double-stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 34

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.