bsm-62034R

DATASHEET

Host: Rabbit

Target Protein: HBEGF

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 1839

Swiss Prot: Q99075

Source: KLH conjugated synthetic peptide derived from human HB EGF

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 23

Cross Reactive Species: Human
Rat

For research use only. Not intended for diagnostic or therapeutic use.