bsm-61831R [Primary Antibody]
IL-23 Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: IL-23

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 51561

Swiss Prot: Q9NPF7

Source: KLH conjugated synthetic peptide derived from human IL 23A

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Associates with IL12B to form the pro-inflammatory cytokine IL-23 that plays different roles in innate and adaptive immunity.Released by antigen-presenting cells such as dendritic cells or macrophages, binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R to activate JAK2 and TYK2 which then phosphorylate the receptor to form a docking site leading to the phosphorylation of STAT3 and STAT4.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 21


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.