bsm-61819R

DATASHEET

Host: Rabbit

Target Protein: GCN2

Modification Site: Thr899

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 440275

Swiss Prot: Q9P2K8

Source: KLH conjugated synthetic peptide derived from human GCN2 around the phosphorylation site of T899

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (EIF2S1/eIF-2-alpha) in response to low amino acid availability.Plays a role as an activator of the integrated stress response (ISR) required for adaptation to amino acid starvation.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 187

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.