bsm-61661R

DATASHEET

Host: Rabbit

Target Protein: FADD

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 14082

Swiss Prot: Q61160

Source: KLH conjugated synthetic peptide derived from mouse Fadd

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 23

Cross Reactive Species: Mouse

For research use only. Not intended for diagnostic or therapeutic use.