bsm-61658R

DATASHEET

Host: Rabbit

Target Protein: RNF8

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 9025

Swiss Prot: O76064

Source: KLH conjugated synthetic peptide derived from human RNF8

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 56

Cross Reactive Species: Human
Rat

For research use only. Not intended for diagnostic or therapeutic use.