bsm-61576R

DATASHEET

Host: Rabbit

Target Protein: RASSF1A

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 11186

Swiss Prot: Q9NS23

Source: KLH conjugated synthetic peptide derived from human RASSF1

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Isoform A interacts with CDC20, an activator of the anaphase-promoting complex, APC, resulting in the inhibition of APC activity and mitotic progression.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 39

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.