bsm-61538R-HRP

DATASHEET

Host: Rabbit

Target Protein: MBD1

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 4152

Swiss Prot: Q9UIS9

Source: KLH conjugated synthetic peptide derived from human MBD1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binding is abolished by the presence of 7-mG that is produced by DNA damage by methylmethanesulfonate (MMS). Acts as transcriptional repressor and plays a role in gene silencing by recruiting ATF7IP, which in turn recruits factors such as the histone methyltransferase SETDB1.

Conjugation: HRP

Excitation/ Emission: N/A

Size: 100ul

Concentration: Lot dependent

Applications: WB(1:300-5000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Predicted Molecular Weight: 67

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.