bsm-61535R-APC

DATASHEET

Host: Rabbit

Target Protein: ZAP70

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 7535

Swiss Prot: P43403

Source: KLH conjugated synthetic peptide derived from human ZAP70

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Regulates motility, adhesion and cytokine expression of mature T-cells, as well as thymocyte development. Contributes also to the development and activation of primary B-lymphocytes. When antigen presenting cells (APC) activate T-cell receptor (TCR), a serie of phosphorylations lead to the recruitment of ZAP70 to the doubly phosphorylated TCR component CD247/CD3Z through ITAM motif at the plasma membrane.

Conjugation: APC

Excitation/ Emission: 650nm/660nm

Size: 100ul

Concentration: Lot dependent

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 70

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.