bsm-61499R

DATASHEET

Host: Rabbit

Target Protein: TLR9

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 54106

Swiss Prot: Q9NR96

Source: KLH conjugated synthetic peptide derived from human TLR9

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides.Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 116

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.