bsm-61491R-APC

DATASHEET

Host: Rabbit

Target Protein: WNT5A

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 7474

Swiss Prot: P41221

Source: KLH conjugated synthetic peptide derived from human Wnt5a

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression.

Conjugation: APC

Excitation/ Emission: 650nm/660nm

Size: 100ul

Concentration: Lot dependent

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 42

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.