bsm-61443R

DATASHEET

Host: Rabbit

Target Protein: Noxa

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 5366

Swiss Prot: Q13794

Source: KLH conjugated synthetic peptide derived from human PMAIP1

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Noxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 6

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.