bsm-61410R

DATASHEET

Host: Rabbit

Target Protein: NUMB

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 8650

Swiss Prot: P49757

Source: KLH conjugated synthetic peptide derived from human NUMB

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Numb acts as a negative regulator of Notch signaling by promoting ubiquitination and degradation of Notch. The protein is asymmetrically segregated into one daughter cell during cell division, producing two daughter cells with different responses to Notch signaling and different cell fates. The localization of Numb can also be regulated by G-protein coupled receptor (GPCR) and PKC signaling.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 71

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.