bsm-61399R-Cy3

DATASHEET

Host: Rabbit

Target Protein: Dnmt1

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 1786

Swiss Prot: P26358

Source: KLH conjugated synthetic peptide derived from human DNMT1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting and development. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: Lot dependent

Applications: WB(1:300-5000)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 183

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.