bsm-61358R

DATASHEET

Host: Rabbit

Target Protein: MGMT

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 4255

Swiss Prot: P16455

Source: KLH conjugated synthetic peptide derived from human MGMT

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 22

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.