bsm-61354R-BF750

DATASHEET

Host: Rabbit

Target Protein: CBL (Tyr774)

Modification Site: Tyr774

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 867

Swiss Prot: P22681

Source: KLH conjugated synthetic peptide derived from human CBL around the phosphorylation site of Y774

Purification: Purified Polyclonal A

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Participates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome.

Conjugation: AbBy Fluor® 750

Excitation/ Emission: 749nm/775nm

Size: 100ul

Concentration: Lot dependent

Applications: WB(1:300-5000)
FCM(1:20-100)

Predicted Molecular Weight: 100

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.