bsm-61337R

DATASHEET

Host: Rabbit

Target Protein: NOTCH4

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 4855

Swiss Prot: Q99466

Source: KLH conjugated synthetic peptide derived from human Notch 4

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 210

Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.