bsm-61152R-Cy3

DATASHEET

Host: Rabbit

Target Protein: APAF1

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 317

Swiss Prot: O14727

Source: KLH conjugated synthetic peptide derived from human APAF 1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: Lot dependent

Applications: WB(1:300-5000)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 142

Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.