bsm-61072R

DATASHEET

Host: Rabbit

Target Protein: Bcl-XL

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 598

Swiss Prot: Q07817

Source: KLH conjugated synthetic peptide derived from human Bcl-xL

Purification: Purified by Protein A.

Storage Buffer: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage: Store at 4°C for short term. Store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Background:

Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane.
Isoform Bcl-X(S) promotes apoptosis.

Size: 100ul

Concentration: Lot dependent

Predicted Molecular Weight: 26

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.