bsm-54373R [Primary Antibody]
Nicastrin (3F10) Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: NCSTN

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 23385

Swiss Prot: Q92542

Source: Synthetic peptide within Human Nicastrin aa 650-750 (C terminal).

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Background:

Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 78


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Lane 1: THP-1 Cell; Probed with Nicastrin (3F10) Monoclonal Antibody (bsm-54373R) at 1:1000, overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.