bsm-54044R [Primary Antibody]
DAZL (5F7) Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: DAZL

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 1618

Swiss Prot: Q92904

Source: Mouse DAZL aa 1-300

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store for 1 year at -20°C from date of shipment. Store for 1 year at -20°C from date of shipment.

Background:

DAZL (deleted in azoospermia-like), an RNA-binding protein that effects spermatogenesis, is an autosomal homolog of the Y chromosome DAZ (deleted in azoospermia). The gene encoding human DAZL maps to chromosome locus 3p24. DAZL, like other members of The DAZ family members are included in germ cells in both male and female gonads. A Thr 54-to-Ala mutation within the RNA-recognition domain of DAZL proteins contributes to spermatogenic failure. Infertility in DAZL knockouts are unable to complete the first meiotic prophase in the first wave of spermatogenesis.

Size: 100ul

Concentration: 1ug/ul

Cross Reactive Species: Human
Mouse
Rat
(WB(1:500-1000), IHC-P(1:50-200))

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Paraformaldehyde-fixed and paraffin-embedded Rat Testis tissue incubated with DAZL (5F7) Monoclonal Antibody (bsm-54044R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.


Paraformaldehyde-fixed and paraffin-embedded Mouse Testis tissue incubated with DAZL (5F7) Monoclonal Antibody (bsm-54044R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.