bsm-54003R
[Primary Antibody]
SFRP1 (2C4) Monoclonal Antibody
DATASHEET
Host: Rabbit
Target Protein: SFRP1
Clonality: Monoclonal
Isotype: IgG
Entrez Gene: 6422
Swiss Prot: Q8N474
Source: Human SFRP1 between 1 to 100 amino acids
Purification: Purified by Protein A.
Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage: Store at -20°C for 12 months.
Background:
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
Size: 100ul
Concentration: 1ug/ul
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Human kidney cells lysates probed with SFRP1 (2C4) Monoclonal Antibody (bsm-54003R) at 1:500 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.