bsm-52831R
[Primary Antibody]
CD74 (2G1) Monoclonal Antibody
DATASHEET
Host: Rabbit
Target Protein: CD74
Clonality: Monoclonal
Isotype: IgG
Entrez Gene: 972
Swiss Prot: P04233
Source: Human CD74 aa 1-200
Purification: Purified by Protein A.
Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage: Store at -20°C for 12 months.
Background:
Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
Size: 100ul
Concentration: 1ug/ul
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Lane 1: Raji cells lysates;Probed with CD74 (2G1) Monoclonal Antibody (bsm-52831R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.
Paraformaldehyde-fixed and paraffin-embedded Human tonsil tissue incubated with CD74 (2G1) Monoclonal Antibody (bsm-52831R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
Paraformaldehyde-fixed and paraffin-embedded Human spleen tissue incubated with CD74 (2G1) Monoclonal Antibody (bsm-52831R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.