DATASHEET
Host:
Rabbit
Target Protein:
NQO1
Clonality:
Recombinant
Isotype:
IgG
Entrez Gene:
1728
Swiss Prot:
P15559
Source:
Full length protein
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Storage:
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Background:
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
PRODUCT SPECIFIC PUBLICATIONS
- Zeba Farooqui . et al. Nrf2 inhibition induces oxidative stress, renal inflammation and hypertension in mice. Clin Exp Hypertens. 2021;43(2):175-18Read more>>
VALIDATION IMAGES
Lane 1: SH-SY-5Y lysates; Lane 2: Mouse kidney lysates; Line 3: Raji lysates ;Probed with NQO1 (8T5) Monoclonal Antibody (bsm-52830R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.
25 ug total protein per lane of various lysates (see on figure) probed with NQO1 monoclonal antibody, unconjugated (bsm-52830R) at 1:2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.