bsm-52678R
[Primary Antibody]
Hsp75 (6C2) Monoclonal Antibody
DATASHEET
Host: Rabbit
Target Protein: Hsp75
Clonality: Monoclonal
Isotype: IgG
Entrez Gene: 10131
Swiss Prot: Q12931
Source: N terminal human Hsp75
Purification: Purified by Protein A.
Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage: Store at -20°C for 12 months.
Background:
Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
Size: 100ul
Concentration: 1ug/ul
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Lane 1: Hela Cells; Lane 2: 293T Cells; Probed with Hsp75 (6C2) Monoclonal Antibody (bsm-52678R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.