bsm-52645R [Primary Antibody]
Delta Opioid Receptor (8A1) Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Delta Opioid Receptor

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 4985

Swiss Prot: P41143

Source: Recombinant protein within Human Delta Opioid Receptor aa 1-100

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.

Size: 100ul

Concentration: 1ug/ul

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Flow cytometric analysis of Sh-sy5y cells with Delta Opioid Receptor (8A1) Monoclonal Antibody (bsm-54334R) at a 1:50 dilution (red) compared with an unlabeled control (cells without incubation with primary antibody; black).


Lane 1: HUVEC Cells; Lane 2: Rat brain; Probed with Delta Opioid Receptor (8A1) Monoclonal Antibody (bsm-52645R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.