bsm-52219M [Primary Antibody]
PIK3R1 (9B3) Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Mouse

Target Protein: PIK3R1

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 5295

Swiss Prot: P27986

Source: Recombinant human PI3-kinase p85 subunit alpha protein, around 600-700aa.

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

Size: 100ul

Concentration: 1ug/ul

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Di Wu. et al. Alpinetin prevents inflammatory responses in OVA-induced allergic asthma through modulating PI3K/AKT/NF-B and HO-1 signaling pathways in mice. Int Immunopharmacol. 2020 Dec;89:107073Read more>>
  • Hanpeng Wu. et al. The release of FB1-induced heterophil extracellular traps in chicken is dependent on autophagy and glycolysis. POULTRY SCIENCE. 2023 Jan;:102511Read more>>
VALIDATION IMAGES

Lane 1: U937; Lane 2: Raji cell lysate probed with PIK3R1 (9B3) Monoclonal Antibody (bsm-52219M) at 1:1000 overnight at 4˚C. Followed by a conjugated secondary antibody.