bsm-52216R [Primary Antibody]
PI 3 Kinase p85 alpha Recombinant Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: PI 3 Kinase p85 alpha

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 5295

Swiss Prot: P27986

Source: Recombinant human PI 3 Kinase p85 alpha protein, around 600-700aa.

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Store at -20°C for 12 months.

Background:

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

Size: 100ul

Concentration: Lot dependent

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Xin Bin. et al. circMTO1/miR-30c-5p/SOCS3 axis alleviates oral submucous fibrosis through inhibiting fibroblastmyofibroblast transition. J ORAL PATHOL MED. 2024 MayRead more>>
VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with PIK3R1 monoclonal antibody, unconjugated (bsm-52216R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.