bsm-51447M [Primary Antibody]
ADA (8C3) Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Mouse

Target Protein: ADA

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 100

Swiss Prot: P00813

Source: This ADA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 287-314 amino acids from the C-terminal region of human ADA.

Purification: Purified by Protein G.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.

Size: 100ul

Concentration: 0.5ug/ul

Predicted Molecular Weight: 41


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Lane 1: Jurkat; Lane 2: MOLT-4; Lane 3: CCRF-CEM cell lysate at 20 µg per lane, probed with bsm-51447M ADA (608CT2.1.3) Monoclonal Antibody at 1:4000 dilution and 4℃ overnight incubation, followed by secondary antibody incubation for 60min at room temperature.