bsm-51393M [Primary Antibody]
NFKBIA (1C1) Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Mouse

Target Protein: NFKBIA

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 4792

Swiss Prot: P25963

Source: Purified His-tagged NFKBIA protein was used to produced this monoclonal antibody.

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Size: 100ul

Concentration: 0.5ug/ul

Predicted Molecular Weight: 36


Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Lane 1: Hela Cell lysates; Lane 2: NIH/3T3 Cell lysates; probed with NFKBIA (1121CT8.6.1) Monoclonal Antibody, unconjugated (bsm-51393M) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.