bsm-51271M [Primary Antibody]
SRC (17AT28) Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Mouse

Target Protein: SRC

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 6714

Swiss Prot: P12931

Source: This Src antibody is generated from mouse immunized with a recombinant protein of full length human SRC.

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Size: 100ul

Concentration: 0.5ug/ul

Predicted Molecular Weight: 60


Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Lane 1: HT29 Cell lysates; Lane 2: Jurkat Cell lysates; probed with SRC (17AT28) Monoclonal Antibody, unconjugated (bsm-51271M) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.